张攀-复旦大学医学遗传研究院

科研队伍

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张攀
博士,助理教授,博士生导师
地址:上海市徐汇区东安路131号


教育经历

2004/09-2008/07 兰州大学, 学士
2008/09- 2014/07 北京生命科学研究所, 博士

工作经历

2014/11-2017/02 Vanderbilt University, 博士后
2017/03-2019/02 UCSD, 博士后
2019/03-2025/02 UCLA, staff research associate

主要研究方向

复杂疾病,人类遗传学,生命组学

代表论文

(1) Patowary A*, Zhang P*, Jops C*, Vuong CK, Ge X, Hou K, Kim M, Gong N, Margolis M, Vo D, Wang X, Liu C, Pasaniuc B, Li JJ, Gandal MJ, de la Torre-Ubieta L (2024): Developmental isoform diversity in the human neocortex informs neuropsychiatric risk mechanisms. Science 384(6698),eadh7688

(2) Zhang P, Omanska A, Ander BP, Gandal MJ, Stamova B, Schumann CM (2023): Neuron-specific transcriptomic signatures indicate neuroinflammation and altered neuronal activity in ASD temporal cortex. Proceedings of the National Academy of Sciences 120 (10) e2206758120

(3) Urresti J*, Zhang P*, Moran-Losada P, Yu N-K, Negraes PD, Trujillo CA, Antaki D, Amar M, Chau K, Pramod AB (2021): Cortical organoids model early brain development disrupted by 16p11. 2 Copy Number Variants in autism. Molecular psychiatry 26:7560-7580

(4) Li ST*, Zhao HQ*, Zhang P*, Liang CY, Zhang YP, Hsu AL, Dong MQ (2019): DAF-16 stabilizes the aging transcriptome and is activated in mid-aged C. elegans to cope with internal stress. Aging cell e12896

(5) Zhang P, Samuels DC, Lehmann B, Stricker T, Pietenpol J, Shyr Y, Guo Y (2015): Mitochondria sequence mapping strategies and practicability of mitochondria variant detection from exome and RNA sequencing data.Briefings in Bioinformatics 17(2):224-32

(6) Zhang P, Lehmann BD, Samuels DC, Zhao S, Zhao YY, Shyr Y, Guo Y (2017): Estimating relative mitochondrial DNA copy number using high throughput sequencing data. Genomics Jul 19

(7) Zhang P, Lehmann BD, Shyr Y, Guo Y (2017): The utilization of formalin fixed-paraffin-embedded specimens in high throughput genomic studies. International Journal of Genomics Article ID 1926304

(8) Zhang P, Samuels DC, Zhao S, Wang J, Shyr Y, Guo Y (2016): Practicability of mitochondrial heteroplasmy detection through an Illumina genotyping array. Mitochondrion 31:75-78

(9) Zhang P, Samuels DC, Wang J, Zhao S, Shyr Y, Guo Y (2016): Mitochondria single nucleotide variation across six blood cell types. Mitochondrion 28:16-22

(10)Zhao HQ*, Zhang P*, Gao H, He X, Dou Y, Huang A, Liu XM, Ye A, Dong MQ and Wei L (2015): Profiling the RNA editomes of wild-type C. elegans and ADAR mutants. Genome Research 25: 66-75