教育经历

2006-2010 武汉大学 本科
2014-2020 清华大学 博士

工作经历

2023年至今 复旦大学长寿与衰老研究所/复旦大学附属中山医院 青年研究员 办公室主任
2020年-2022年 清华大学药学院 助理研究员
2010年-2012年 葛兰素史克研发部 科学家

主要研究方向

线粒体突变与衰老的机制研究，线粒体与脑衰老疾病的基础和转化研究

代表论文

(1) Pang, K*., Jiang R., Zhang W., Yang Z., Li LL., Shimozawa M., Tambaro S., Mayer J., Zhang B., Li M., Wang J., Liu H., Yang A., Chen X., Liu J., Winblad B., Han H., Jiang T., Wang W., Nilsson P., Guo W., Lu B. An App knock-in rat model for Alzheimer's disease exhibiting Aβ and tau pathologies, neuronal death and cognitive impairments. Cell Research 32(2):157-175 (2022).

(2) Chen ZY., Zheng WJ., Pang, K#., Xia DB., Gao LX., Wang H#. Weakly-supervised learning analysis of Aβ plaque distribution in whole rat. Frontiers in Neuroscience (2023).

(3) Pang, K*., You, H., Chen, Y., Chu, P., Hu, M., Shen, J., Guo, W., Xie, C., and Lu, B. MagR Alone Is Insufficient to Confer Cellular Calcium Responses to Magnetic Stimulation. Front Neural Circuits 11, 11(2017).

(4) Xiao H*., Pang, K*., Liu,.X., Zhou,J., Zhu Jun# and Yuan, Hao#. Novel roles for CREG1 in hematopoiesis revealed by single cell RNA sequencing. Cell and Bioscience (2025).

(5) Jiang Y*., Li LL*., Pang, K*., Liu J., Chen B., Yuan J., Chen Xi., Lu B and Han H. Synaptic degeneration in the prefrontal cortex of a rat AD model revealed by volume electron microscopy. Journal of Molecular Cell Biology 012 (2022).

(6) Guo, W*., Pang, K*., Chen, Y., Wang, S., Li, H., Xu, Y., Han, F., Yao, H., Liu, H., Lopes-Rodrigues, V., Sun D., Shao J., Shen J., Dou Y., Zhang W., You H., Wu W., Lu B. TrkB agonistic antibodies superior to BDNF: Utility in treating motoneuron degeneration. Neurobiology of Disease 132, 104590 (2019).

(7) Zhuo L, Pang K, Dai J, Wu B, Wang J, Xu H, Yang S, Liu Z, Niu R, Yu P, Wang W. The neurophysiological mechanisms of medial prefrontal-perirhinal cortex circuit mediating temporal order memory decline in early stage of AD rats. Neurobiology of Disease 199:106584 (2024).

(8) Liu H, Mei F, Ye R, Han X, Wang S, Ding Y, Zhi Y, Pang K, Guo W, Lu B. APOE3ch alleviates Aβ and tau pathology and neurodegeneration in the human APPNL-G-F cerebral organoid model of Alzheimer's disease. Cell Research 34(6):451-454 (2024).

(9) Chang, S., Li, LL., Hong, B., Liu, J., Xu, YX., Pang, K., Zhang, LN., Han, H., Chen, X. An intelligent workflow for sub-nanoscale 3D reconstruction of intact synapses from serial section electron tomography. Bmc Biology 21(1):198 (2023).

(10) Wang, TW., Gong, J., Wang, Y., Liang, Z., Pang, K., Wang, JS., Zhang, ZH., Zhang, CY., Zhou, Y., Li, JC., Wang, YN., Zhou, YJ. Differences in Non-suicidal Self-injury Behaviors between Unipolar Depression and Bipolar Depression in Adolescent Outpatients. Current Medical Science 10.1007 (2023).

(11) Shen, J., Sun, D., Shao, J., Chen, Y., Pang, K., Guo, W., and Lu, B. Extracellular Juxtamembrane Motif Critical for TrkB Preformed Dimer and Activation. Cells. 19; 8(8):932 (2019).

(12) Huang, Y., Huang, X., Zhang, L., Han, F., Pang, K., Li, X., and Shen, J.Y. Magnesium boosts the memory restorative effect of environmental enrichment in Alzheimer's disease mice. CNS Neurosciecne & Therapeutics 24, 70-79 (2018)